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Unleashing High-Throughput Reaction Screening

Brought to you by Unchained Labs

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Overview

Maximizing Throughput, Robustness and Analytical Depth for Shotgun Proteomics

A successful high-throughput approach to reaction screening requires a rational and systematic exploration of a broad set of variables to achieve optimization. Even with the aid of high-throughput screening tools, it’s still unlikely that all the possible combinations of reaction variables a process chemist desires can be screened. A well-planned high-throughput approach enables scientists to more clearly see the “big picture,” quickly abandon suboptimal strategies, and rapidly pinpoint advantageous conditions.

Key Learning Objectives

  • How to explore relevant reaction variables and achieve process optimization in an iterative, high-throughput fashion.
  • A case study on an early discovery program involving installing sterically challenging moieties via C-C coupling chemistry.
Brought to you by:
Unchained Labs