C&EN White Papers | Good Things Come in Small Particles: How Size Matters in Liquid Chromatography

Good Things Come in Small Particles: How Size Matters in Liquid Chromatography

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Overview

Tracing the history of liquid chromatography techniques development, this white paper compares the performance and applications of columns packed with different stationary phase. Specifically, the paper focuses on the superficially porous particles (SPPs) columns, highlighting several column types and their growing applications in traditional pharmaceutical, biopharma, and environmental industries.

Key Objectives:

Columns packed with superficially porous particles (SPPs) offer advantages over fully porous particles.
In liquid chromatography, particlesâ€™ morphology and compositions play an important role in separation efficiency and scalability.
Liquid chromatography techniques are advancing beyond pharmaceutical and biopharma industries offering solutions for environmental testing.

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