Analyzing lipid nanoparticle composition using liquid chromatography

Analyzing lipid nanoparticle composition using liquid chromatography

Brought to you by Agilent Technologies

Overview

Lipid nanoparticles (LNPs) have emerged as promising delivery vehicles for nucleic acids in the pharmaceutical industry. To ensure safety and efficacy of the final drug product, the lipid components need analytical characterization of composition, ratio, and degradation. The Agilent 1290 Infinity II Prime Bio LC enables you to do just that. Download this application demonstrating the analysis of the lipid components of patisaran (trade name Onpattro). Optimal separation of the four LNP components with excellent peak shapes, precision, and sensitivity was achieved. The Agilent 1290 Infinity II Prime Bio LC enables you to do just that. Download this application demonstrating the analysis of the lipid components of patisaran (trade name Onpattro). Optimal separation of the four LNP components with excellent peak shapes, precision, and sensitivity was achieved.

Key Objectives

Composition and structure of LNPs
How to achieve best LC separation for the LNP components
How to use the evaporative light-scattering detection for universal detection

Brought to you by:

Please complete the form to download the app note.

Forwarded this link? Clear the form

Email Address*

Title

First Name*

Last Name*

Company*

Job Level*

Address 1*

City*

State*

Zip / Post Code*

Country*

Business Phone*

Agilent wants to keep in touch with you. Please let us know your preference.

Yes, I would like to be contacted via phone or email by an Agilent representative.

Yes, I would you like to receive email information from Agilent about products, services and events.

I would like to receive more information on products and services from the American Chemical Society

*For full details of how Agilent will treat your information please view Agilentâ€™s privacy policy.

*By submitting this form, you agree to receive more information on related products and services from the American Chemical Society (ACS Publications) and its sponsor via email. ACS takes your privacy seriously. For more information, please see the ACS Privacy Policy .