Accelerating Drug Discovery & Development by Unlocking the Stereochemistry of Chiral Molecules:

the Power of VCD

DATE

March 2, 2022

TIME

8:00 a.m. PST, 11:00 a.m. EST, 16:00 GMT, 17:00 CET

Duration: 60 Minutes

Overview

Determining absolute configuration is critical in drug discovery and development but is often a challenge and a rate limiting step. The current gold standard is X-ray crystallography which requires growth of a single crystal. Also, the Xray methodology is often expensive and time consuming. The maturation of Vibrational Circular Dichroism (VCD) makes it ideal alternative to streamline and accelerate the process. VCD is performed in solution, requires no crystallization and has been proven with the characterization of over 10,000 molecules.

This webinar presents real-life examples of how VCD fits into the routine analytical lab for medicinal chemistry and will outline best practices for VCD, from sample preparation through data collection to stereochemical structure.

Key Learning Objectives:

How VCD fits into the routine pharma workflow and the medicinal chemical laboratory
How to determinate absolute configuration of chiral molecules in solution, without crystallization
How to easily combine computational chemistry with experimental measurements
Best practices for VCD, from sample preparation through data collection to stereochemical structure

Who Should Attend:

Medicinal chemists
Laboratory managers/VPs
Anyone who works with chiral molecules

Brought to you by:

Speakers

Yanan He
Principle Investigator for PDS-CMC Analytical,
GSK

Rina Dukor
President & CEO,
BioTools

Jeff Huber
Contributing Editor,
C&EN Media Group

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