Design and Optimization of Biologics Driven

by Physics-Based Computational Modeling

June 15, 2021
10:00 a.m. PDT, 1:00 p.m. EDT, 18:00 BST, 19:00 CEST
Duration: 60 Minutes


In this webinar, we will address the important role that computational modeling can play in accelerating the discovery and development of novel biologics. The presentation will highlight recent advances in Schrödinger's protein modeling capabilities and their application to common protein design problems encountered in real-world projects. Topics covered will include strategies for protein property prediction followed by optimization through engineering. In particular, we will discuss quantitatively accurate prediction of the effects of residue mutations on protein thermal stability and protein-protein binding affinity using FEP+ technology, and the recent developments of the method to further improve accuracy and reliability. 

Brought to you by:


Dr. Eliud Oloo
Senior Principal Scientist,
Dr. Lingle Wang
Vice President,
Scientific Development,
Jeff Huber
Contributing Editor,
Scientific Development,
C&EN Media Group


*By submitting this form, you agree to receive more information on related products and services from the American Chemical Society (ACS Publications) via email, in accordance with the ACS Privacy Policy.

© 2021 American Chemical Society, 1155 16th St NW, Washington, DC 20036, USA. View our Privacy Policy