Design and Optimization of Biologics Driven

by Physics-Based Computational Modeling

DATE
June 15, 2021
TIME
10:00 a.m. PDT, 1:00 p.m. EDT, 18:00 BST, 19:00 CEST
Duration: 60 Minutes

Overview

In this webinar, we will address the important role that computational modeling can play in accelerating the discovery and development of novel biologics. The presentation will highlight recent advances in Schrödinger's protein modeling capabilities and their application to common protein design problems encountered in real-world projects. Topics covered will include strategies for protein property prediction followed by optimization through engineering. In particular, we will discuss quantitatively accurate prediction of the effects of residue mutations on protein thermal stability and protein-protein binding affinity using FEP+ technology, and the recent developments of the method to further improve accuracy and reliability. 

Brought to you by:
Schrödinger

Speakers

Dr. Eliud Oloo
Senior Principal Scientist,
Schrödinger
Dr. Lingle Wang
Vice President,
Scientific Development,
Schrödinger
Jeff Huber
Contributing Editor,
Scientific Development,
C&EN Media Group

Registration

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