Rapid Detection of Mutagens with Direct MS


  • Date
    October 16, 2019
  • Time
    8:00 a.m. PDT / 11:00 a.m. EDT / 16:00 BST / 17:00 CEST - Duration: 60 Minutes

Date : October 16, 2019
Time : 8:00 a.m. PDT / 11:00 a.m. EDT / 16:00 BST / 17:00 CEST - Duration: 60 Minutes
  • Overview

    Volatile compounds are common impurities in pharmaceutical products and are often of concern due to their toxicity (e.g. as mutagens or genotoxins). SIFT-MS is a new analytical tool for real-time, selective, and economical trace gas and headspace quantification of volatile compounds, including chromatographically challenging ones such as formaldehyde, formic acid, and ammonia. But how do you approach analytical method validation for SIFT-MS so that the data can be used to support regulatory requirements? By applying a strategic approach in accordance with ICH Q2(R1) Guidelines to direct SIFT-MS methods – and utilizing formaldehyde analysis as a case study – successful validation is readily achieved.

    Join us for this webinar to learn more about how SIFT-MS works, how it speeds up analysis, and how it can be validated successfully in accordance with ICH Q2(R1) Guidelines suitable for pharmaceutical applications such as regulatory submissions where GMP compliance is essential.

    Sponsored by:


    Syft Technologies

  • Speakers

    Vaughan Langford, PhD
    Principal Scientist,
    Syft Technologies
    Mark Perkins, PhD
    Senior Applications Chemist,
    Anatune Limited
    Celia Arnaud
    Senior Correspondent,
    C&EN