The evolving role of mass spectrometry in drug discovery

DATE

September 16, 2021

TIME

8:00 a.m. PDT, 11:00 a.m. EDT, 16:00 BST, 17:00 CEST Duration: 60 Minutes

Overview

Mass spectrometry is increasingly playing a central role as a platform to investigate biological pathways, quantify protein abundancies, look for interactions between proteins, and investigate protein modifications in healthy and disease cells. Furthermore our ability to quantify the interactions of small molecules with proteins by mass spectrometry has become mainstream and we now have MS-based lead generation platforms available. The increasing sensitivity and applicability of mass spectrometry to different molecule types has also enabled widespread use for investigating absorption, distribution and metabolism of mew modalities such as antibody drug conjugates and oligonucleotides, becoming a key technique supporting the development of these therapeutics.

In this webinar we will review the state of the art in these main areas:

Mass spectrometry as a tool for target identification and validation, with a focus on proteomics
Small molecule lead generation with mass spectrometry, with a focus on affinity selection mass spectrometry
Distribution, metabolism and pharmacokinetics of new modalities through the application of mass spectrometry

Who Should Attend:

Drug discovery scientists in academia, biotech and the pharmaceutical industry. Chemists, biologists, pharmacologists, toxicologists, DMPK scientists of all levels

Brought to you by:

Speakers

Wenzhang Chen
Senior Director,
WuXi AppTec

Nan Zhao
Principle Scientist III, LTD DMPK,
WuXi AppTec

Dave Madge
Vice President,
WuXi AppTec

Penny Jia
AS-MS Project Leader,
WuXi AppTec

Jeff Huber
Contributing Editor,
C&EN Media Group

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