Challenges and opportunities in Peptide Drug Conjugates (PDCs)

DATE

December 14, 2022

TIME

8:00 a.m. PST, 11:00 a.m. EST, 16:00 GMT, 17:00 CET - Duration: 60 Minutes

Overview

PDCs have gained extensive attention as they are being proven successful in treating cancers recently with their superior target-specific delivery. PDCs combine peptides and linker-toxins, their development and manufacturing require comprehensive synthetic chemistry, process development, analytical method development, and manufacturing capabilities for both highly potent small molecules and peptides, which often bring technical challenges, especially during scale-up. Here we discuss how we overcome challenges and demonstrate opportunities through case studies.

Key Learning Objectives:

The key role of peptides in targeted drug delivery
The design strategy of PDCs
Challenges and solutions in PDC development and manufacturing
One-stop PDC platform at WuXi STA from discovery to GMP manufacture

Who Should Attend:

Biotechnology Innovators
Oncologist
Pharmaceutical & Fine Chemists
Peptide Researchers
Drug Manufacturer

Brought to you by:

Speakers

Yonghui Ge, Ph.D.,
Executive Director, Process R&D,
WuXi STA, a WuXi AppTec Company

Hui Liao, Ph.D.,
Director of Peptide Discovery Group,
WuXi STA, a WuXi AppTec Company

Kelly McSweeney,
Contributing Editor,
C&EN Media Group

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