Quantifying 1,4-Dioxane in Personal Care, Cosmetic and Cleaning Products

DATE

March 31, 2021

TIME

8:00 a.m. PDT, 11:00 a.m. EDT, 16:00 BST, 17:00 CEST - Duration: 60 Minutes

Overview

1,4-Dioxane is an emerging industrial chemical of concern and probable human carcinogen found as a contaminate in personal care, cosmetic and cleaning products. To curb the release of the compound into the environment, new regulatory limits on the concentration of 1,4-dioxane in these products are proposed by state governments. Thus, the need for new analytical methods for testing these products is critical.

Two methods will be described for the analysis of 1,4-dioxane in consumer product matrices including hand soaps, shampoos, and laundry detergents. The methods will include review of a headspace GC/MS workflow and a solid-phase microextraction GC/QQQ workflow. Method performance criteria for both workflows will be presented to ensure quality assurance and quality control requirements are met.

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Speakers

Katherine Castor
Research Scientist III,
California Dept of Toxic Substances Control Environmental Chemistry Laboratory

Dr. Castor received her PhD in Chemistry from McGill University in Montreal under the supervision of Dr. Hanadi Sleiman. After relocating to the greater Los Angeles area, she spent several years as an analytical biochemist for Huntington Medical Research Institutes where she researched lipid biomarkers for the early detection of Alzheimer’s Disease using GC/MS. In 2017, she moved to the DTSC where she focuses on method development using advanced technologies for the quantification of emerging chemicals of concern.

Sujan Fernando
Analytical Laboratory Director,
Research Professor Center for Air and Aquatic Resources Engineering and Science at Clarkson University

Dr. Fernando received his Ph.D. from McMaster University (Ontario, Canada). His Ph.D. research focused on assessing the exposure of humans to combustion products using multidimensional chromatography and ultra-high resolution mass spectrometry. Dr. Fernando served as a Mass Spectrometry Specialist at the McMaster Regional Centre for Mass Spectrometry for nearly 10 years prior to moving to Clarkson University.
At Clarkson, Dr. Fernando manages the CAARES Analytical Facility which focuses on the analysis of emerging environmental contaminants.

Alexandra Taylor
Associate Editor,
C&EN

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