Crystal Growth & Design Webinar Series - Trapping and Playing with Liquids Inside Crystals

How can crystalline materials be designed to store and release liquid active ingredients (L-AI)? The release profile can be related to the solid-state arrangement of the material, offering a strong and rational tool to afford a vast range of materials for controlled delivery of L-AI. Cocrystallization is shown to be a powerful method to control the release of liquid ingredients in the environment, thanks to the engineering of ad hoc intermolecular interactions which strengthen or weaken the tendency of the ingredient to be retained inside the solid matrix. Similarly, L-AI have been encapsulated within adaptable cavities of Metal Organic Frameworks intentionally designed to uptake such guests; the evolution in time of the supramolecular arrangement of the nano-confined guests in the cavities has been monitored by SCXRD and related to the observed selectivity of the material towards different liquid guests.

You will hear from Alessia Bacchi, full Professor of Chemistry at the University of Parma, and she served as the President of the European Crystallographic Association from 2015-2018.

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