Learn more about this year's winners, Prof. Matthias Gehringer and Prof. Amanda Wolfe, as they present their research in this webinar moderated by the Journal of Medicinal Chemistry Editor-in-Chief Prof. Craig Lindsley, and ACS Division of Medicinal Chemistry Vice Chair Nicole Goodwin.
Prof. Craig Lindsley; Editor-in-Chief, Journal of Medicinal Chemistry
00:07:55
Harnessing the power of undergraduate researchers in antibiotic development
Prof. Amanda Wolfe; University of North Carolina Asheville, United States
00:42:30
Covalent Inhibitors Targeting the Protein Kinases' Cysteinome
Prof. Matthias Gehringer; University of Tübingen, Germany
01:25:00
Q&A Panel
Profs. Craig Lindsley, Amanda Wolfe, and Matthias Gehringer
01:31:40
Closing Remarks
Prof. Craig Lindsley; Editor-in-Chief, Journal of Medicinal Chemistry
WINNERS WEEK 2024 ON-DEMAND
WEBINAR
2024 Journal of Chemical & Engineering Data Lectureship Awards
This award celebrates one outstanding early career scientist/engineer conducting experimental or computational research in thermophysical properties and phase equilibria.
This awards webinar features the three winners of the 2024 Advances in Measurement Science Awards and the inaugural 2024 Early Career Investigator Award in Analytical Chemistry.
GlaxoSmithKline Distinguished Professor in Molecular and Chemical Biology
University of North Carolina Asheville, United States
Amanda began her chemistry career as an undergraduate at North Carolina State University in Raleigh, North Carolina, working in Professor Christian Melander’s laboratory on the development of 2-aminoimidazole bacterial biofilm inhibitors. She then attended graduate school at Scripps Research in La Jolla, California where she worked in Professor Dale Boger’s laboratory on the synthesis and evaluation of anti-cancer prodrugs derived from the duocarmycin family of natural products. Amanda then began her independent career at the University of North Carolina Asheville (UNC Asheville) in 2013 as an Assistant Professor of Medicinal Chemistry and earned tenure in 2018. In 2022, Amanda was designated as the GlaxoSmithKline Distinguished Professor in Molecular and Chemical Biology and promoted to full Professor in 2023. At UNC Asheville, researchers in the Wolfe laboratory, which has had 58 undergraduate, 4 high school, and 2 post-doctoral researchers to date, broadly focus on small molecule antibiotic development targeting multi-drug resistant Pseudomonas aeruginosa and Acinetobacter baumannii. The Wolfe laboratory has been funded by the National Institute of Allergy and Infectious Diseases, Research Corporation for Science Advancement, the Camille and Henry Dreyfus Foundation, the North Carolina GlaxoSmithKline Foundation, and the North Carolina Biotechnology Center.
Professor of Medicinal Chemistry and Chemical Biology
University of Tübingen, Germany
Matthias studied chemistry at the Karlsruhe Institute of Technology (KIT; Germany), the Ecole Nationale Supérieure de Chimie de Montpellier (ENSCM; France), and the University of Heidelberg (Germany). He obtained his doctorate from the University of Tübingen (Germany) where he worked on reversible and irreversible inhibitors of the protein kinase JAK3. As a postdoc at the Swiss Federal Institute of Technology (ETH) Zürich, he focused on the total synthesis of complex natural products from the mycolactone family. In 2019, he was appointed Assistant Professor for Medicinal Chemistry at the Institute of Pharmaceutical Sciences, University of Tübingen, and Associate Investigator in the Cluster of Excellence "Image Guided and Functionally Instructed Tumor Therapies (iFIT)". His research is in the areas of Medicinal Chemistry and Chemical Biology focuses primarily on covalent protein kinase inhibitors and novel approaches for the covalent targeting of cysteine and other amino acids.