C&EN White Paper
Solid-Core Particles: Application to Small Molecule LC Analysis

Brought to you by MAC-MOD Analytical

The current generation of solid core particles for LC analysis were introduced in 2006 and provide higher efficiency separations than equivalently sized fully porous particles. Since then, their use for the analysis of both small and large molecules has increased steadily, in a wide variety of analytical fields, to drive high performance separations and increases in laboratory throughput. This white paper focusses on the application of solid core particles to small molecule analysis. It begins by introducing the concept of solid core particles, their morphology, history of development and current methods of synthesis, before moving on to discuss the theory behind the performance advantages they offer. Finally, example applications that demonstrate how these particles can be used to provide solutions for some of the analytical challenges faced by the modern chromatography laboratory are discussed.

Key Objectives:

Participants Will:
  • Learn how to apply solid-core particles to small molecule analyses
  • Learn the performance advantages of solid-core particles
  • Review example solid-core small molecule applications

Brought to you by:
MAC-MOD Analytical
Please complete the form to download the white paper.
*By submitting this form, you agree to receive more information on related products and services from the American Chemical Society (ACS Publications) and its sponsor via email. ACS takes your privacy seriously. For more information, please see the ACS Privacy Policy .

Copyright © 2024 American Chemical Society | 1155 Sixteenth Street NW | Washington, DC 20036 | View our Privacy Policy