The chromatographic applications include purification and analysis of VLPs and antibody drugs, LC/MS and HILIC analysis of oligonucleotides, amino acids and other proteins. The initial proof of concept of these biopharmaceutical applications displays recent advances in this growing field.
- Norovirus VLP were purified from silkworms and investigated as a proof of concept
- LC/MS analysis of various oligonucleotides were studied without the use of an ion-pair reagent
- Additives and aggregates in antibody drugs were isolated using simple methods
- Choline, acetylcholine, neurotransmitters, oral antidiabetic drugs and aminoglycoside antibiotics were analyzed on a single column