Unleashing High-Throughput Reaction Screening

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Overview

Reaction screening requires the systematic exploration of a broad set of relevant reaction variables to achieve optimization. A well-planned approach using high-throughput screening tools allows scientists to clearly see the “big picture”, quickly abandon disadvantaged routes and rapidly pinpoint advantageous and impactful conditions to focus on.

Key Learning Objectives

How to explore relevant reaction variables and achieve process optimization in an iterative, high-throughput fashion.
About a case study on an early discovery program using an automated high-throughput approach to install sterically challenging moieties via C-C coupling chemistry.