Iron plays a vital role in the maintenance of life, being central to various cellular processes, from respiration to gene regulation, and iron storage proteins such as DNA binding proteins under starvation (Dps) ensure that nontoxic forms of iron are readily available for these processes. This review examines the multifarious properties of Dps through relevant biochemical and structural studies with a focus on iron storage and ferroxidation, as well as its role as an iron donor to iron-sulfur clusters found in many biological processes.
Sunanda Margrett Williams and Dipanker Chatterji, University of London (U.K.) and Indian Institute of Science, Bangalore (India)
ACS Omega 2023, 8, 38, 34299–34309