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A Digital Time-lapse, Bright Field Technology to Drive Faster, Higher Throughput Bioanalysis

Chiara Canali*, Erik Spillum, Martin Valvik, Niels Agersnap, Tom Olesen

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Cell Culture Basics HandBook

The constant need to develop more rapid and cost-effective technologies for accurate, sensitive and specific detection in biological samples is a driving force behind the integration of new sample preparation tools, automation and informatics across the bioanalytical workflow. These technologies have potential applications in different fields of research ranging from microbiology, toxicology and medicinal chemistry to the pharmaceutical and cosmetic industries, 1 as well as food and environmental safety. 2 We present the design characteristics, operational features and key advantages of a new digital, time-lapse, bright field technology with demonstrated uses and great potential across a range of applications involving bioanalysis of microbial and mammalian cells.

Key Learning Objectives

  • Integrating Automation and Informatics to Advance Large-Scale Cell Biology
  • Existing Technologies: Challenges and Limitations
  • Comparing Optical Technology for Imaging Live Cells
  • New Digital, Time-Lapse Technology
  • Algorithms Enable Segmentation, Growth Kinetics, and Cell Proliferation and Migration Analyses
  • Proven Applications and Future Developments