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Affinity Tags Head Toward the Vaccination Clinic

Brought to you by Thermo Fisher Scientific


Researchers typically avoid using affinity tags in the purification of therapeutic proteins. Recently, one very short affinity tag—just four amino acids long—proved its worth for purifying a malaria vaccine candidate for clinical trials. This has opened the door to a range of novel protein-based malaria vaccine candidates, which are now either in or progressing toward clinical trials.     

Key Learning Objective

  • Example of C-tag being used to accelerate vaccine development
  • C-tag system is a viable technology for GMP-compliant manufacture of therapeutic proteins
  • Understanding how the C-tag affinity tag system functions

Brought to you by: 
Thermo Fisher Scientific

 Affinity Tags Head Toward the Vaccination Clinic

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